Application

Western blot: Recommended dilution: 1:500 (2 µg/mL)
Expected Molecular Weight: 74.5 kDa
Note: Bands may be present at a higher molecular weight due to glycosolation.

Research CategoryStem Cell Research

This Anti-MELK Antibody, clone 6C1.3 is validated for use in WB for the detection of MELK.

Research Sub CategoryNeural Stem Cells

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Melk, (Maternal Embryonic Leucine Zipper Kinase) is a serine-threonine kinase of the snfI/AMPK family that is expressed in developing neuroepithelium, self-renewing neural stem cells and granule cell precursors. It is also considered an important brain tumor marker, being highly expressed in gliobastoma, astrocytomas, and medulablastomas.

Immunogen

MELK Recombinant protein.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Purified immunoglobulin in PBS, pH 7.0. Contains 0.1% sodium azide.

Storage and Stability

1 year at 2-8 °C from date of shipment

Target description

74.5 kDA; glycosylations may result in higher MW bands in western blot.